Accepted by Scopus and Clarivate Analytics to be indexed in Science Citation Index Expanded, JCR, Current Contents and Biological Abstracts

CDC/ C Goldsmith, P Feorino, EL Palmer, WR McManus

HIV-infected cells are frequently clonally expanded after prolonged antiretroviral therapy: implications for HIV persistence

Author List
F Maldarelli

Abstract

HIV infection is controlled but not eradicated by combination antiretroviral therapy (cART), and persistence during therapy represents a substantial barrier to strategies to eradicate infection. The nature of persistence is uncertain, and a number of mechanisms have been proposed to explain HIV persistence in vivo, including low-level HIV replication, sanctuary sites for HIV-infected cells, and latent HIV residing within long-lived cells.

Article Category

HIV cure research

Article Type

Reviews

Posted Date

01-10-2015

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