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Immune checkpoints and the HIV-1 reservoir: proceed with caution

Author List
Rikke Olesen
Steffan Leth
Rasmus Nymann
Lars Østergaard
Ole S Søgaard
Paul W Denton
Martin Tolstrup

Abstract

Successfully identifying and targeting immune checkpoints on latently HIV-1-infected CD4+ T cells could be a key component in HIV-1 eradication therapies. We propose that distinguishing between total and memory CD4+ T cell subsets is fundamental when interpreting data regarding HIV-1 DNA and immune checkpoints.

Article Category

HIV cure research

Article Type

Viewpoints

Posted Date

01-07-2016

Tables & Figures

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