Immune checkpoints and the HIV-1 reservoir: proceed with caution

Author List
Rikke Olesen
Steffan Leth
Rasmus Nymann
Lars Østergaard
Ole S Søgaard
Paul W Denton
Martin Tolstrup


Successfully identifying and targeting immune checkpoints on latently HIV-1-infected CD4+ T cells could be a key component in HIV-1 eradication therapies. We propose that distinguishing between total and memory CD4+ T cell subsets is fundamental when interpreting data regarding HIV-1 DNA and immune checkpoints.

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HIV cure research

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