
Immune checkpoints and the HIV-1 reservoir: proceed with caution
Author List |
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Rikke Olesen |
Steffan Leth |
Rasmus Nymann |
Lars Østergaard |
Ole S Søgaard |
Paul W Denton |
Martin Tolstrup |
Abstract
Successfully identifying and targeting immune checkpoints on latently HIV-1-infected CD4+ T cells could be a key component in HIV-1 eradication therapies. We propose that distinguishing between total and memory CD4+ T cell subsets is fundamental when interpreting data regarding HIV-1 DNA and immune checkpoints.
Published
Article Category
HIV cure research
Article Type
Viewpoints
Posted Date
01-07-2016