Accepted by Scopus and Clarivate Analytics to be indexed in Science Citation Index Expanded, JCR, Current Contents and Biological Abstracts

A collaborative, multidisciplinary approach to HIV transmission risk mitigation during analytic treatment interruption

Author List
Michael J Peluso
Lynda Dee
Danielle Campbell et al.


Analytic treatment interruptions (ATI s) are currently the standard for assessing the impact of experimental interventions aimed at inducing sustained antiretroviral therapy (ART)-free remission in trials related to HIV cure. ATI s are associated with substantial risk to both study participants and their sexual partner(s). Two documented HIV transmissions occurring in the context of ATI s have been recently reported, but recommendations for mitigating the risk of such events during ATI s are limited. We outline a practical approach to risk mitigation during ATI studies and describe strategies we are utilising in an upcoming clinical trial that may be applicable to other centres.

Article Category

HIV cure research

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